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Flora and fauna of the Lake Stechlin areahate (InsP3). DAG activates protein kinase C (PK-C) and InsP3 mobilizes intracellular calcium. Both tumor promoting phorbol esters (TPA) which activate PK-C directly and calcium ionophores which mobilize intracellular calcium bypass inositol phospholipid breakdown. We recently reported that the inte
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Georges Gorin,Didier Morend,André Puginifferent regions of haemopoietic tissue. In the leg shielding experiments, cellularity, spleen colony-forming unit (CFU-S) content and proliferative activity return to normal in the shielded limb long before they do in the rest of the animal. (5). Following phenylhydrazine (PHZ), demand for erythroi
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Dingtian Yang,Yunlin Zhang,Weimin Chenrogeny which can differentiate along lineage-specific pathways. Although much is known about the humoral factors involved in regulating the proliferation and differentiation of committed hematopoietic progenitor cells, the role of humoral factors in the proliferation of pluripotent hematopoietic ste
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M. J. M. Hootsmans,J. E. Vermaatutant. The etiology has been presumed due to a defect in the ability the marrow stem cells to differentiate into normally functioning osteoclasts. Data are not available to prove that replacing only the osteoclast precursor (an unidentified cell) will cure the disorder. To test whether marrow stroma
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Environmental Concerns and Management,f the stromal tissue which controls hemopoiesis (1–7). It has been, however, impossible to determine conclusively which of the stromal cell types comprising this complex microenvironment tissue is mediating the observed functions. The requirement for pure cell populations for any further experimenta
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