Titlebook: Examination of the in vitro Regenerative and Neuroprotective Potential of Short Chain Fatty Acid But; Clarissa Annabella Lohmann Book 2024

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Aims,fect in MS, which improved the disease phenotype. Similar results were also demonstrated for propionate in CIDP patients (Yoon et al., 2018). In addition, propionate was shown to have an anti-oxidative and neuroregenerative effect on Schwann cells and DRG in . studies (Grüter et al., 2023a).

Provenance

Introduction

Methods,ere kept in an open cage system with a maximum population of 4 animals per cage (cage type IV). In the closed and darkened rooms, a light-dark rhythm of 12/12 hours was artificially induced, with twilight phases in between.

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Results, 16,000 µM, 32,000 µM). The evaluation took place, measuring the outgrowth of the neurites in µm and plotting it using GraphPad. In Figure 5.1 shown a significant reduction of the neurites in the sodium butyrate concentrations from 2,000 µM to 32,000 µM.

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Discussion,of life and at sometimes life expectancy is reduced, which can lead to death. A better understanding of these diseases is needed to develop better treatments to increase patients’ life expectancy and improve their quality of life.