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Titlebook: Engrams; A Window into the Me Johannes Gräff,Steve Ramirez Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive licen

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All IEGs Are Not Created Equal—Molecular Sorting Within the Memory Engramsystematically reviewing published work on engram ensemble cells defined by the following four major IEGs: Fos, Npas4, Arc, and Egr1. By comparing and contrasting these likely different components of the memory engram, we hope to gain a better understanding of the logic and significance behind the molecular sorting process for memory functions.
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Memory Storage in Distributed Engram Cell Ensemblesch for physical correlates of memory, the memory engram, has been a longstanding priority in modern neurobiology. Advanced genetic approaches have led to the localization of engram cells in a few brain regions, including the hippocampus and cortex. Additionally, engram cells exhibit learning-induced
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The Role of Prefrontal Ensembles in Memory Across Time: Time-Dependent Transformations of Prefrontaljection-specific circuit manipulation and activity-dependent labeling, have illuminated how mPFC memory ensembles are reorganized over time. This chapter discusses the implications of new findings for traditional theories of memory, such as the systems consolidation theory and theories of memory eng
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Unveiling Transcriptional and Epigenetic Mechanisms Within Engram Cells: Insights into Memory Formatnges in distributed neuronal ensembles across various brain regions. These ensembles are known as engrams, and the cells that constitute them are referred to as engram cells. Recent advancements in techniques for labeling and manipulating neural activity have facilitated the study of engram cells th
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