Titlebook: Emerging Paradigms for Antibiotic-Resistant Infections: Beyond the Pill; Mayank Gangwar,Gopal Nath Book 2024 The Editor(s) (if applicable)

正式演说

Association and Contribution of Dentistry in Creating and Sharing the Burden of Antibiotic-Resistantnthetic bacteriostatic/bactericidal antibiotics lead to a golden phase of human health where bacterial infections were conveniently confronted. However, in due course microbes evolved to develop resistance against these “magic bullets” and there is continuous decline in antibiotic susceptibility. Th

Panacea

Culmination

Reviving Phage Therapy: A Novel Approach to Treat Respiratory-Associated Infectionsnotable application of phages is in the treatment of bacterial infections, where phages’ lytic capabilities enable them to effectively eliminate bacterial populations. In the face of rising antibiotic resistance, especially multi-, extensive-, and pan-drug-resistant bacteria, there is an urgent need

实现

CRISPR–Cas Against Antimicrobial-Resistant Pathogenstems offer opportunities for studying the microbial consortia, controlling industrial fermentation, and treating infections resistant to various medications. They possess the capacity to eliminate particular bacterial strains in a sequence-specific manner, both quantitatively and selectively.

alleviate

流行

不容置疑

The Rise of Antibiotic Resistance: A “Silent Killer”HO), an estimated 5.2 million people in the Western Pacific region will die due to drug-resistant bacterial infections. This increase in resistance is attributed to changes in bacteria that render antibiotics less effective. Resistance is rising for both first-line drugs (such as ciprofloxacin, ampi

SLING

Alternative Approaches to Counter Multidrug-Resistant Bacterial Pathogensgenome editing utilizing clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein (Cas), reduction of bacterial pathogenesis by anti-virulence strategies such as targeting specialized secretion systems, regulating virulence gene expression and toxin production, an

易发怒

Anti-Quorum-Sensing Techniques: A Potential Strategy to Manage Antibiotic Resistanceacteria use the peptide derivatives of these signaling molecules, whereas Gram-negative bacteria use the fatty acid derivatives. Because of this, we must prevent quorum sensing, which is accomplished through various types of quorum-sensing inhibitors (QSIs). Natural and synthetic QSIs are essential

支柱

Beyond Antibiotics: Pioneering Strategies in Infection Control to Counter Antibiotic Resistance’s Rifield of advanced nonantibiotic therapies. Each therapy was meticulously analyzed, considering the mechanisms of action, applications, and challenges. We explored case studies and advancements to provide an up-to-date and nuanced perspective on the state of nonantibiotic therapies. Our findings unde