Titlebook: Extremophilic Cyanobacteria For Novel Drug Development; Sikha Mandal,Jnanendra Rath Book 2015 Springer International Publishing Switzerlan

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https://doi.org/10.1007/978-3-030-46270-3chapter. Cyanobacteria also produce a wide range of compounds that revealed apoptotic properties. Potential cyanobacterial compounds with apoptotic properties and their use as drug delivery system with cellular targets are also discussed.

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Secondary Metabolites of Cyanobacteria and Drug Development,mixture of NRPS and polyketide synthases (PKS) modules. We discussed the important metabolites of cyanobacteria and their biosynthetic metabolic pathways. Various recent approaches in extraction of novel secondary metabolites from cyanobacteria are discussed with novel biosynthetic gene clusters found in them.

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Anticancer Drug Development from Cyanobacteria,chapter. Cyanobacteria also produce a wide range of compounds that revealed apoptotic properties. Potential cyanobacterial compounds with apoptotic properties and their use as drug delivery system with cellular targets are also discussed.

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Book 2015nism originated, produce oxygen that leads to evolution of life on the earth, how their survival strategies in extreme climatic conditions lead to diverse metabolic pathways, and the opportunity to use them to develop novel drugs. The book is comprised of five chapters, starting with the origin of c

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Introduction,e several structural and functional modifications. They had to adapt various environmental conditions and during this process they come up as one of the extremophilic organism. In this chapter, the diversity of cyanobacteria in various extreme habitats is discussed with examples of dominant species.

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Glycoconjugates of Cyanobacteria and Potential Drug Development From Them,surface as sheaths, capsules and/or slimes, or as released polysaccharides (RPS). In this chapter we discuss the chemical characteristics of glycans of cyanobacteria, their biosynthesis, use in glycotherapy and drug delivery device and potential for vaccine development.

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Anticancer Drug Development from Cyanobacteria,cells. Cyanobacterial metabolites exhibit a wide range of biological effects and some of these metabolites possess potential cytotoxic activities to different mammalian cell lines. The various cyanobacterial compounds with potential anticancer properties and their cytotoxicity are discussed in this

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Issues and Challenges of Drug Development from Cyanobacteria,nt stages of clinical trial. Despite many potent biological activities, very few cyanobacterial compounds have entered clinical trials. We discuss various challenges facing drug development from them and their prospects as ideal candidates for novel drug discovery.