Titlebook: Extracellular Vesicles; From Bench to Bedsid Qian Wang,Lei Zheng Book 2024 China Science Publishing & Media Ltd (Science Press) 2024 Extrac

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Methods for the Isolation of Extracellular Vesiclesations for choosing a proper method when dealing with different scientific questions: (1) how much co-isolating contaminants can be tolerated; (2) how important is the ease of use for conducting large-scale clinical or basic research; and (3) how critical is the EV yield for subsequent analysis.

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Book 2024 exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicula

TERRA

Mongi Boughzala,Hassouna Moussaengineering approaches have been developed, with a few functionalized EVs planned for clinical trials. In this chapter, we summarize recent advances in EV surface functionalization and discuss the advantages and limitations to each strategy. Furthermore, we also propose future directions for accelerating the clinical use of these strategies.

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lls may modulate gene expression patterns. Animal models of EV treatment are required for functional validation in vivo. Thus, the functions of cell-derived EVs and engineered EVs need to be validated in vivo using animal models to facilitate their application in the clinical setting.

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Technologies for the Surface Functionalization of Extracellular Vesiclesengineering approaches have been developed, with a few functionalized EVs planned for clinical trials. In this chapter, we summarize recent advances in EV surface functionalization and discuss the advantages and limitations to each strategy. Furthermore, we also propose future directions for accelerating the clinical use of these strategies.

错误

Methods for Analysis of Extracellular Vesicle Functionslls may modulate gene expression patterns. Animal models of EV treatment are required for functional validation in vivo. Thus, the functions of cell-derived EVs and engineered EVs need to be validated in vivo using animal models to facilitate their application in the clinical setting.

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