书目名称 | Extracellular Matrix in Development |
编辑 | Douglas W. DeSimone,Robert P. Mecham |
视频video | |
概述 | Gives a comprehensive and up to date overview on the field.Written by experts in the field.Covers the role of ECM in development from all angles.Includes supplementary material: |
丛书名称 | Biology of Extracellular Matrix |
图书封面 |  |
描述 | .Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.. |
出版日期 | Book 2013 |
关键词 | Amphibian gastrulation; Epithelia; Growth factor signaling; Organ morphogenesis; Skeleton; Stem cells |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-35935-4 |
isbn_softcover | 978-3-642-42740-4 |
isbn_ebook | 978-3-642-35935-4Series ISSN 0887-3224 Series E-ISSN 2191-1959 |
issn_series | 0887-3224 |
copyright | Springer-Verlag Berlin Heidelberg 2013 |