Titlebook: Extracellular Matrix Omics; Sylvie Ricard-Blum Book 2020 Springer Nature Switzerland AG 2020 Extracellular matrix.Quantitative proteomics.

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Characterization of Proteoglycanomes by Mass Spectrometry,py a unique niche in biology. They have varied and essential roles as structural and regulatory molecules in numerous physiological processes and disease pathology. In regard to cellular context, some link the interior of the cell to the extracellular matrix (ECM) as transmembrane or membrane-anchor

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Historical Overview of Integrated GAG-omics and Proteomics,oteoglycans (PGs). GAGs and PGs play vital roles in ECM-related processes such as cell migration, proliferation, adhesion, and differentiation. Among the . technologies, including genomics, transcriptomics, and proteomics, glycomics is the least mature. Over the past two decades, with efforts from g

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Extracellular Matrix Networks: From Connections to Functions,Ricard-Blum, Cold Spring Harb Perspect Biol 3:a004978, 2011), glycosaminoglycans (GAGs) and proteoglycans (PGs) (Iozzo and Schaefer, Matrix Biol 42:11–55, 2015; Karamanos et al., Chem Rev 118:9152–9232, 2018). We review here the major methods used to identify and characterize ECM protein, glycosamin