| 书目名称 | Extracellular ATP and adenosine as regulators of endothelial cell function | | 副标题 | Implications for hea | | 编辑 | Evgenia Gerasimovskaya,Elzbieta Kaczmarek | | 视频video | | | 概述 | The first book with a unique focus on the effects of extracellular nucleotides and adenosine in endothelial cells..Describes regulatory role of extracellular nucleotides and adenosine in angiogenesis, | | 图书封面 |  | | 描述 | .Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. ..This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. .This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological conditions, i.e. pregnancy, hypoxia, hypertension, inflammation and diabetes. .In the book’s 12 chapters, the role of purinergic signaling in endothelium-dependent tissue perfusion, regulation of endothelial barrier function, and angiogenesis are discussed. The mechanisms of ATP release and its role in intercellular communication are also presented. .In addition, the book provides the most up to date mechanisms of extracellular nucleotide metabolism by purine-converting ecto-enzymes and their c | | 出版日期 | Book 2010 | | 关键词 | Activation; Extracellular ATP; Nucleotide; Purine; Pyrimidine; cells; endothelium; metabolism; regulation; ti | | 版次 | 1 | | doi | https://doi.org/10.1007/978-90-481-3435-9 | | isbn_softcover | 978-94-007-9680-5 | | isbn_ebook | 978-90-481-3435-9 | | copyright | Springer Science+Business Media B.V. 2010 |
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发表于 2025-3-21 16:41:57
