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Titlebook: Experimental Models of Cardiovascular Diseases; Methods and Protocol Kiyotake Ishikawa Book 2024Latest edition The Editor(s) (if applicable

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1064-3745 ental Models of Cardiovascular Diseases: Methods and Protocols, Second Edition .aims to provide detailed and practical protocols that will be valuable tools for researchers in cardiology to conduct their research..978-1-0716-3848-4978-1-0716-3846-0Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Geometric Methods and Optimization Problemsn process employs physical or chemical methods, or a combination of them, to remove the cellular components of tissues and organs while preserving the architecture and composition of the ECM. Depending on the methodology used, the decellularized ECM (dECM) is then suitable for research or clinical a
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Alexander Kushkuley,Zalman Balanovly work in physiological settings, where tissues and organs are interconnected and moderating drug responses. To address this challenge and advance personalized medicine, researchers have turned to human-induced pluripotent stem (iPS) cells, which can be differentiated to resemble the human heart in
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,Cohomologie non ramifiée des quadriques,eart failure and death. Despite intense research in the last decades, PAH remains an incurable disease with high morbidity and mortality. New directions and therapies to improve understanding and treatment of PAH are desperately needed. The pathological mechanisms leading to this fatal disorder rema
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https://doi.org/10.1007/978-1-4471-4360-4ture models, such as human-induced pluripotent stem cell-derived cardiomyocytes and 3D multicell type organoid culture methods, the detection of adverse cardiac events prior to human clinical trials has improved. However, there are still numerous therapeutics whose adverse cardiac effects are not de
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Special Applications in Surface Fittingly useful due to the anatomical and physiological similarities between porcine and human hearts, providing an experimental platform to investigate cardiac disease or assess donor heart viability for transplantation. This chapter presents an in-depth discussion of the model’s components, including th
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