Titlebook: Exercise, Respiratory and Environmental Physiology; A Tribute from the S Guido Ferretti Book 2023 The American Physiological Society 2023 E

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,Margaria’s Revolution: A Novel Energetic View of Muscular Contraction,a gas-sustaining life, on energy transformations, and on lactate as an end-product of metabolism during exercise. The ensemble of this knowledge is the basis on which Archibald Vivian Hill and Otto Meyerhof created the first comprehensive theory of the energetics of muscular exercise, centered aroun

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The Energetics and Biomechanics of Walking and Running,the energetics of walking and running is discussed. In this context, after having introduced Margaria’s concept of energy cost, the effects of incline, of the terrain, of pathological gaits and of body mass and aging are treated. In the second part, the contribution of the School of Milano to the kn

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Respiratory Mechanics,led to the estimate of the mechanical work of breathing and the corresponding energy cost in order to match the metabolic requirement. A full analysis of the statics of the respiratory system was performed thanks to the refined technique of esophageal recording. The concept of mechanical stability a

Optic-Disk

,The Air–Blood Barrier,s” are being described allowing to exert a strict control on the amount of the extravascular water that is kept at minimum in physiological conditions to favor oxygen uptake. The key role of the macromolecular structure network of the lung interstitial tissue is described to guarantee a minimal micr

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A School Goes to Altitude,are firstly described. The studies performed during the expedition to Mount Kanjut-Sar, Karakorum, in 1957, and during the Italian Expedition to Mount Everest in 1973 are reported. This expedition generated a highly celebrated article, on the factors limiting oxygen transport on Mount Everest. The s