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Titlebook: Excitatory Amino Acids; Peter J. Roberts,Jon Storm-Mathisen,Harry F. Bradf Book 1986 The Editors and the Contributors 1986 amino acid.huma

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Glutamate Transport in the Synaptic Vesicle,naptic vesicles in an ATP-dependent but Na+-independent manner. Pharmacological evidence suggests that the vesicular glutamate uptake is driven by an electrochemical proton gradient generated by a proton-pump ATPase. The ATP-dependent vesicular uptake is highly specific for glutamate, and the glutam
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Presynaptic Receptors for Excitatory Amino Acid Transmitters,l nervous system, and this has led to the characterisation of at least three subtypes (viz. those activated by N-methyl-Daspartate (NMDA), quisqualate and kainate) on the basis of electrophysiological studies (see Watkins, this volume). In contrast to the postsynaptic receptors, relatively little at
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Anatomical Organization of NMDA, Kainate and Quisqualate Receptors,he CNS. Autoradiography allows a quantitative description of anatomical and pharmacological properties of binding sites in specific CNS locations which can then be correlated to function. Receptors in a single dendritic field can be both biochemically characterized and rigorously studied by electrop
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