书目名称 | Evolving Concepts in Sepsis and Septic Shock | 编辑 | Peter Q. Eichacker,Jérôme Pugin | 视频video | | 丛书名称 | Perspectives on Critical Care Infectious Diseases | 图书封面 |  | 描述 | Much research over the past 30 to 40 years has shown that theinflammatory response, while critical for host defense duringmicrobial infection, may itself play a central role in thepathogenesis of sepsis. Although key mediators responsible for thisinjury have been identified, efforts clinically to augment ourconventional antimicrobial and supportive therapies during sepsis withagents modulating the inflammatory response have been unsuccessful. Asa result, the mortality associated with this lethal syndrome,especially when complicated by shock, has remained persistently high.Unfortunately, during this same period of time, the incidence ofsepsis has accelerated as other fields of medicine have reliedincreasingly on therapies that predispose to infection..While frustrating, overall this experience in the field of sepsis hasnot been without value. Most importantly, it has helped define onseveral different levels the complexity of the septic patient.Recognizing and addressing this complexity as discussed by each of thecontributors to .Evolving Concepts in Sepsis and Septic Shock. maynow provide new inroads into the treatment of sepsis. | 出版日期 | Book 2001 | 关键词 | Atmen; Sepsis; antimicrobial; bacteria; infection; infections; infectious diseases | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4615-1581-4 | isbn_softcover | 978-1-4613-5625-7 | isbn_ebook | 978-1-4615-1581-4Series ISSN 1568-2501 | issn_series | 1568-2501 | copyright | Springer Science+Business Media New York 2001 |
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