Titlebook: Evolutionary Tinkering in Gene Expression; Marianne Grunberg-Manago,Brian F. C. Clark,Hans G. Book 1989 The Editor(s) (if applicable) and

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tRNA Genes - Tinkering in Organization and Expression?,s-acting factors from lower to higher eukaryotes. Like other genes that are transcribed by RNA polymerase III, tRNA genes contain intragenic control regions that direct their transcription. For tRNA genes, these highly conserved internal control regions (the A and B boxes) coincide with sequences of

exceptional

Transcriptional Control by Retroviral LTR Regions,ty and potency of pathogenic properties. Some viruses induce lymphomas with high incidence and a latency period of a few months when injected into newborn mice of various inbred strains, whereas others show a weaker and less specific pathogenicity. The pathogenic effects of these weaker viruses incl

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The Human Immunoglobulin K Locus and its Evolution,(K) locus is described. The locus consists of variable, joining and constant (V., J., C.) gene segments and comprises at least 2 Mb (mega-base pairs) of DNA. Up to now 81 of the perhaps about 100 V. genes and pseudogenes have been isolated on cosmid clones. Several contigs have been constructed cove

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Alternative Splicing to Tissue Specific Splicing - An Evolutionary Pathway?, species of pre-messenger RNA which are synthesized in various tissues or in one tissue at various stages of development, but which are spliced to give slightly different collections of exons in each tissue or at each stage of development. We wish to contrast such .: in the latter, various collectio