书目名称 | Evolution of Extracellular Matrix |
编辑 | Fred W. Keeley,Robert P. Mecham |
视频video | |
概述 | Gives a comprehensive and up to date overview on the field.Written by experts in the field.First book to look in detail on the evolution of ECM.Includes supplementary material: |
丛书名称 | Biology of Extracellular Matrix |
图书封面 |  |
描述 | .The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.. |
出版日期 | Book 2013 |
关键词 | Angiogenesis; Cell Adhesion; Collagen; Elastin; Fibrin; Fibrosis |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-36002-2 |
isbn_softcover | 978-3-642-43037-4 |
isbn_ebook | 978-3-642-36002-2Series ISSN 0887-3224 Series E-ISSN 2191-1959 |
issn_series | 0887-3224 |
copyright | Springer-Verlag Berlin Heidelberg 2013 |