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Titlebook: Etomidate; An Intravenous Hypno A. Doenicke Book 1977 Springer-Verlag Berlin Heidelberg 1977 Etomidat.clinical trial.drug.pain.research.sho

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书目名称Etomidate
副标题An Intravenous Hypno
编辑A. Doenicke
视频video
丛书名称Anaesthesiologie und Intensivmedizin‘ Anaesthesiology and Intensive Care Medicine
图书封面Titlebook: Etomidate; An Intravenous Hypno A. Doenicke Book 1977 Springer-Verlag Berlin Heidelberg 1977 Etomidat.clinical trial.drug.pain.research.sho
描述The question how to induce general anaesthesia without problems has been asked repeatedly by anaesthetists and pharmacologists. P. A. JANSSEN developed etomidate and published this substance in 1971 as "a potent short-acting and relatively atoxic intravenous hypnotic agent in rats". In 1974 after several years of experimental and clinical trial the barbiturate-free hypnotic etomidate (soon marketed as Hypnomidate) was introduced to numerous auditors at the occasion of the IV. European Congress of Anaesthesiologists in Madrid. As the authors extended their essays, the actuality of the present book is given. The conclusion mentions the new solution of etomidate base in 35 % propylene glycol. It is expected that the disadvantageous effects - venous pain during injection and associated involuntary muscle movement- will largely be eliminated by using the new formula of etomidate after premedication of fentanyl. Mlinchen, August 1977 Alfred DOENICKE TABLE OF CONTENTS The Experimental Pharmacology of Etomidate, a New Potent, Short-Acting Intravenous Hypnotic (R. S. RENEMAN and P. A. JANSSEN) •. . . . •• 1 Protein Binding of Etomidate (G. A. MANNES and A. DOENICKE) ••••. . . 6 The Effect o
出版日期Book 1977
关键词Etomidat; clinical trial; drug; pain; research; shock
版次1
doihttps://doi.org/10.1007/978-3-642-66787-9
isbn_softcover978-3-540-08485-3
isbn_ebook978-3-642-66787-9Series ISSN 0171-1814
issn_series 0171-1814
copyrightSpringer-Verlag Berlin Heidelberg 1977
The information of publication is updating

书目名称Etomidate影响因子(影响力)




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书目名称Etomidate被引频次




书目名称Etomidate被引频次学科排名




书目名称Etomidate年度引用




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书目名称Etomidate读者反馈学科排名




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The EEG after Etomidate,sis of the available anaesthesiological experience, it seemed justified to test the usefulness of etomidate in combined balanced anaesthesia by further investigations with electroencephalographic control. In our earlier publication (DOENICKE et al., 1973) we described the essential similarity of the
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,Haemodynamic Effects of Etomidate — a New Hypnotic — in Patients with Myocardial Insufficiency,terest in this new imidazole-carboxylate hypnotic. All of the clinical investigations have been performed in volunteers or patients with a normal cardiovascular system (BRÜCKNER et al., 1974; KETTLER et al., 1974). In these patients etomidate had only little influence on haemodynamic parameters.
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Haemodynamics, Myocardial Function, Oxygen Requirement, and Oxygen Supply of the Human Heart after ed great hopes with regard to their less pronounced effects on respiration and circulation. Some examples are the preparations used in neuroleptanalgesia (NLA), propanidid, ketamine, the steroid anaesthetic Althesin, and the new short- acting barbiturate methohexital.
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The Influence of R 26 490 (Etomidate Sulfate) on Ventilation and Gas Exchange,Investigations in animals and humans (BRÜCKNER et al., 1974; DOENICKE et al., 1973) followed. In comparison with Althesin, ketamine, methohexitone and propanidid, etomidate caused only minimal side effects on cardiovascular system (BRÜCKNER et al., 1974). The present study was undertaken in order to
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Etomidate Anaesthesia for Cardioversion,n cardiac arrhythmias. Therapeutic reliability has grown substantially since the introduction of DC-defibrillation controlled by the cardiac action cycle (Kouwenhoven et al., 1954; Lown et al., 1962, 1964; McDonald et al., 1964), as opposed to AC-defibrillation (Alexander et al., 1961; Zoll et al.,
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