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Titlebook: Etiology of Acute Leukemias in Children; Juan Manuel Mejía-Aranguré Book 2016 Springer International Publishing Switzerland 2016 Hemato-on

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,Model for the Origin of Acute Leukemias in Children: Interaction of Three Factors—Susceptibility, Emia occurs and how it develops; the proposed model, being relatively simpler, attempts to specify the moment when a child develops acute leukemia. The causes of childhood leukemia have not yet been identified because the theoretical basis of the search has been at fault. The risk factors for acute l
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Molecular Origin of Childhood Acute Lymphoblastic Leukemia,ent of genome-wide profiling techniques for copy number alterations (CNAs) as well as sequence mutations, we have thoroughly characterized many different genetic subtypes of ALL. Each subtype harbors alterations activating leukemogenic pathways and differs in prevalence, prognosis, cell type, and tr
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