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Titlebook: Essential and Non-essential Metals; Carcinogenesis, Prev Anuradha Mudipalli,Judith T. Zelikoff Book 2017 The Editor(s) (if applicable) and

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书目名称Essential and Non-essential Metals
副标题Carcinogenesis, Prev
编辑Anuradha Mudipalli,Judith T. Zelikoff
视频video
概述Provide current state of research on metals in human biology, health and disease.A state of the art molecular details delineating the metal related cancers with synthesis and analyses of the available
丛书名称Molecular and Integrative Toxicology
图书封面Titlebook: Essential and Non-essential Metals; Carcinogenesis, Prev Anuradha Mudipalli,Judith T. Zelikoff Book 2017 The Editor(s) (if applicable) and
描述.This book aims to present current state of understanding of the role of metals in human health and disease. As it will be difficult to cover all of the metals, about two scores of them, the authors will instead provide a detailed analysis of a select set of essential (.Calcium, Magnesium, Selenium, Iron, copper and Zinc) and non-essential metals (Nickel, Chromium, Cadmium and Arsenic, Tungsten and Asbestos.). Each chapter will have a dedicated section focusing on the binary role that some of these metals play, their carcinogenic and cancer therapeutics, by integrating epidemiological, experimental evidence with special emphasis and focus on molecular mechanisms involved in these processes. The biological analysis will also include emerging lines of evidence such as micro RNAS, kinase families, receptors, endoplasmic, mitochondrial players and epigenetics. As part of integrating the human, experimental and mechanistic data, as well as a detailed analysis into the modes of actionfor different cancer outcomes will be discussed in each chapter wherever deemed feasible. These approaches are ones in which no other book in this area has attempted to do..
出版日期Book 2017
关键词Cancer; Carcinogen; Metal; Molecular medicine; Treatment
版次1
doihttps://doi.org/10.1007/978-3-319-55448-8
isbn_softcover978-3-319-85664-3
isbn_ebook978-3-319-55448-8Series ISSN 2168-4219 Series E-ISSN 2168-4235
issn_series 2168-4219
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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发表于 2025-3-21 20:59:17 | 显示全部楼层
Essential and Non-essential Metals978-3-319-55448-8Series ISSN 2168-4219 Series E-ISSN 2168-4235
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Edwin L. Prien Jr.,Hibbard E. Williams active sites in selenoproteins. In humans, 25 selenoproteins have been identified, and most of them function as important antioxidant enzymes and play important roles in the detoxification of reactive oxygen species (ROS). Selenoproteins are critical for normal physiology. Dysregulation and malfunc
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SpringerBriefs in Speech Technologyon of contaminated drinking water or food, or by inhalation of fumes from burning coal. Arsenic does not induce point mutations like a classic DNA-damaging mutagen. The carcinogenic mechanism is unclear, but evidence exists supporting DNA repair inhibition, stem cell expansion, reactive oxygen gener
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https://doi.org/10.1007/978-1-349-23809-5ndustries are exposed to Cr(VI). Epidemiological studies indicate particulate Cr(VI) compounds are the most potent carcinogens, resulting in sinusoid and lung tumors following inhalation. Although Cr(VI) is well established as a human lung carcinogen, the mechanism of carcinogenesis remains unknown.
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