书目名称 | Essential and Non-essential Metals | 副标题 | Carcinogenesis, Prev | 编辑 | Anuradha Mudipalli,Judith T. Zelikoff | 视频video | | 概述 | Provide current state of research on metals in human biology, health and disease.A state of the art molecular details delineating the metal related cancers with synthesis and analyses of the available | 丛书名称 | Molecular and Integrative Toxicology | 图书封面 |  | 描述 | .This book aims to present current state of understanding of the role of metals in human health and disease. As it will be difficult to cover all of the metals, about two scores of them, the authors will instead provide a detailed analysis of a select set of essential (.Calcium, Magnesium, Selenium, Iron, copper and Zinc) and non-essential metals (Nickel, Chromium, Cadmium and Arsenic, Tungsten and Asbestos.). Each chapter will have a dedicated section focusing on the binary role that some of these metals play, their carcinogenic and cancer therapeutics, by integrating epidemiological, experimental evidence with special emphasis and focus on molecular mechanisms involved in these processes. The biological analysis will also include emerging lines of evidence such as micro RNAS, kinase families, receptors, endoplasmic, mitochondrial players and epigenetics. As part of integrating the human, experimental and mechanistic data, as well as a detailed analysis into the modes of actionfor different cancer outcomes will be discussed in each chapter wherever deemed feasible. These approaches are ones in which no other book in this area has attempted to do.. | 出版日期 | Book 2017 | 关键词 | Cancer; Carcinogen; Metal; Molecular medicine; Treatment | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-55448-8 | isbn_softcover | 978-3-319-85664-3 | isbn_ebook | 978-3-319-55448-8Series ISSN 2168-4219 Series E-ISSN 2168-4235 | issn_series | 2168-4219 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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