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Titlebook: Epstein-Barr Virus and Human Disease · 1990; D. V. Ablashi,A. T. Huang,Kristinë L. Ablashi Book 1991 Springer Science+Business Media New Y

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Relationship of the EBV Lytic Activator Zta to the bZIP Family of Cellular Transactivatorsnts the pivotal viral protein in the reactivation process. In earlier studies we utilized a bacterially expressed Zta in DNAseI footprinting assays to identify six Zta binding sites in the .HI-H divergent promoter (2). The sequences protected by Zta binding were TGTGTAA, TGAGCAA, TGTGCAA and TGTGTCA
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Trans-regulation of the Early MS Gene of EBV and Its Dependence on the Host Cellransiently active cellular factors control the expression of lytic viral proteins. Besides activation of the repressed BZLF1 immediate early gene (F. Schwarzmann, manuscript in preparation) additional regulatory events are involved, e.g. the expression of two further immediate early products, BRLF1
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Induction and Regulation of Expression of the Epsteinbarr Virus DNA Polymerase Gene (1). This determination was predicted by the close sequence homology between this ORF and the coding sequences for the HSV-1 and HCMV DNA polymerase genes (2, 3, 4) as well as the close match between the predicted amino-acid composition of the BALF-5-encoded protein and the amino-acid composition o
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Book 1991ocess. In an effort to attract both basic and clinical scientists to the same meeting for purposes of scientific exchange and fostering a closer interaction between these individuals, a series of international symposia was initiated in 1984. The first meeting was held in Loutraki, Greece, and was at
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Transcriptional Regulation of an Epstein-Barr Virus Nuclear Antigen Gene Promotererating similar leader sequences in transcripts arising from either promoter (7, figure la). It appears to be the case that only one of these promoters is active in any given clonal cell line (8) but the mechanism of promoter selection remains totally obscure. In order to identify elements that modu
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