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Titlebook: Epstein-Barr Virus and Associated Diseases; Proceedings of the F P. H. Levine,D. V. Ablashi,S. D. Kottaridis Conference proceedings 1985 Ma

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发表于 2025-3-21 17:17:23 | 显示全部楼层 |阅读模式
书目名称Epstein-Barr Virus and Associated Diseases
副标题Proceedings of the F
编辑P. H. Levine,D. V. Ablashi,S. D. Kottaridis
视频video
丛书名称Developments in Medical Virology
图书封面Titlebook: Epstein-Barr Virus and Associated Diseases; Proceedings of the F P. H. Levine,D. V. Ablashi,S. D. Kottaridis Conference proceedings 1985 Ma
描述It has been slightly more than two decades since the Epstein-Barr virus (EBV) was discovered by Prof. M.A. Epstein and his colleagues at the University of Bristol in their search for the causative agent of Burkitt‘s lymphoma. For several years EBV was a "virus in search of a disease." The first documentation that EBV was pathogenic for humans was in 1969 when Drs. Gertrude and Werner Henle identified it as the causative agent for infectious mononucleosis. Seroepidemiologic and biochemical studies subsequently linked EBV to Burkitt‘s lymphoma (BL), nasopharyngeal carcinoma (NPC), and more recently to the X-linked lymphoproliferative syndrome. With its widespread pattern of infection and a predilection for producing clinical signs and symptoms in only certain individuals, EBV has provided a model for many other candidate oncogenic viruses, including papilloma viruses, herpes simplex, and HTLV/LAV. In 1975, an international workshop was sponsored by the National Cancer Institute to address the problem of EBV production, thus facilitating basic research on the virus. This proved to be the last international meeting on EBV for almost a decade. In the past, progress in both clinical and
出版日期Conference proceedings 1985
关键词antibody; antigen; cancer; cell; documentation; immunodeficiency; immunology; immunosuppression; infection; i
版次1
doihttps://doi.org/10.1007/978-1-4613-2625-0
isbn_softcover978-1-4612-9641-6
isbn_ebook978-1-4613-2625-0
copyrightMartinus Nijhoff Publishing, Boston 1985
The information of publication is updating

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Siobhan Rockcastle,Marilyne Andersenibodies are detected by indirect immunofluorescence (Henle and Henle, 1966). With this method, however, antigen complexes rather than single proteins are detected. In the present study, we examined sera of EBV-infected persons for antibodies against the membrane protein gp 250 using a radioimmuno-precipitation assay.
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Brief Communication The Significance of Antibodies Against the Epstein-Barr Virus-Specific Membrane ibodies are detected by indirect immunofluorescence (Henle and Henle, 1966). With this method, however, antigen complexes rather than single proteins are detected. In the present study, we examined sera of EBV-infected persons for antibodies against the membrane protein gp 250 using a radioimmuno-precipitation assay.
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The “Family Study” Approach to Investigating the Role of Genetic Factors in Nasopharyngeal Carcinomas and interpretation of the data. These methods could be utilized in a hospital setting where such patients are seen, thereby improving our knowledge of the relative contributions of genetics and environment in the etiology of these diseases.
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Relapsing, Recurrent, and Chronic Infectious Mononucleosis in the Normal Hostied my attention for the past few years, but which are incompletely addressed in the literature. These include the rather provocative issues of relapse, recurrence, and chronicity of EBV infection in the normal host.
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Immune Assessment of Patients with Chronic Active EBV Infection (CAEBV). Circulating immune complexes were present in 50% of patients studied. T-cell suppression of Ig production persisted in patients. Production of IL-2, IFN γ and NK activity were diminished in patients. Whether these latter differences are due to or result in the ongoing disease is not understood.
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