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Titlebook: Epstein Barr Virus Volume 2; One Herpes Virus: Ma Christian Münz Book 2015 The Editor(s) (if applicable) and The Author(s), under exclusive

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Non-human Primate Lymphocryptoviruses: Past, Present, and Futurebridization studies provided the first glimpses of the closely related herpesviruses that belonged to the same gamma-1 herpesvirus, or lymphocryptovirus, genus, as EBV. Over the years, detailed molecular and sequence analyses of LCVs that infect humans and other NHPs revealed similar colinear genome
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EBV Infection of Mice with Reconstituted Human Immune System Componentsrus establishes persistent infection in the majority of adult humans, but fortunately causes EBV-associated diseases only in few individuals. This is an incredible success story of the human immune system, which controls EBV infection and its transforming capacity for decades. A better understanding
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EBNA2 and Its Coactivator EBNA-LP2 and EBNA-LP with EBNA1, EBNA3A, -3B, and -3C as well as LMP1, LMP2A, and LMP2B. The focus of this review will be to discuss the current understanding of how two of these proteins, EBNA2 and EBNA-LP, contribute to EBV-mediated B-cell growth transformation.
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Epstein-Barr Virus Lytic Cycle Reactivationn of viral progeny. In addition, the chapter highlights the potential role of lytic infection in disease development and current attempts to purposely induce lytic infection as a therapeutic approach.
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