Titlebook: Epigenetics in Oncology; Jianjun Chen,G. Greg Wang,Jun Lu Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive licen

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American Studies oder Amerikanistik?ngs on the engagement of epitranscriptomic pathways, especially the ones associated with .-methyladenosine (m.A), in the regulation of cancer metabolism and the surrounding microenvironment. We also discuss the promising therapeutic approaches targeting RNA modifications for anti-tumor therapy.

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https://doi.org/10.1007/978-3-030-00575-7 RNA metabolism to drive oncogenic or tumor-suppressive cellular pathways. m.A RNA methylation also plays dynamic roles within both immune cells and tumor cells to mediate the anti-tumor immune response. Finally, an emerging area of research within epitranscriptomics studies the role of m.A RNA meth

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American Television on British Screensso recognized as guanosine by the splicing and translation machineries, resulting in mRNA alternative splicing and protein recoding. Therefore, A-to-I RNA editing is an important mechanism that causes and regulates “RNA mutations” in both normal physiology and diseases including cancer. In this chap

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American Writers And Radical Politics1900-39ational modification regulates functionality of EZH2 and PRC2, and how PRC2 and other epigenetic pathways crosstalk. Lastly, we will briefly touch on advances in targeting EZH2 and PRC2 dependence as cancer therapeutics.

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RNA Modifications in Cancer Metabolism and Tumor Microenvironmentngs on the engagement of epitranscriptomic pathways, especially the ones associated with .-methyladenosine (m.A), in the regulation of cancer metabolism and the surrounding microenvironment. We also discuss the promising therapeutic approaches targeting RNA modifications for anti-tumor therapy.

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Recent Advances of RNA m6A Modifications in Cancer Immunoediting and Immunotherapypathological processes, including immune system development and cancer pathogenesis. Therefore, a deeper understanding of the mechanisms by which RNA modifications impact the cancer immunoediting process can provide insight into the mechanisms of resistance to immunotherapies and the strategies that