Titlebook: Epigenetics and Neuroendocrinology; Clinical Focus on Ps Dietmar Spengler,Elisabeth Binder Book 2016 Springer International Publishing AG,

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From Vulnerability to Neurotoxicity: A Developmental Approach to the Effects of Stress on the Brain s effects on brain structures involved in cognition and mental health. In this selective review of the literature, we show that specific effects on the brain, behavior, and cognition emerge as a function of the timing and the duration of exposure to stress. We present the effects of stress on the br

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Dynamic Regulation of Chromatin Modification and Transcription by GR and the Steroid Receptorsaintain optimal physiological function. Understanding how quickly transcription factors interact with DNA; how these interactions effect and are influenced by levels of DNA methylation and histone modifications; and how long these interactions persist for has led to new insights into the fundamental

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Glucocorticoid-Dependent Epigenetic Regulation of ,ric diseases. In particular, chronic exposure to stress or glucocorticoids (GCs) has been shown to elicit symptoms of depression and mania in humans and animals. One of the key modulators of the stress response is a chaperone protein called Fk506-binding protein 5, or FKBP5, that regulates intracell