| 书目名称 | Epigenetics and Cancer |
| 编辑 | Fazlul H. Sarkar |
| 视频video | |
| 概述 | First book on epigenetics and cancer.Covers epigenetic regulation of mRNA.Covers epigenetic regulation of miRNA in multiple cancers.Includes supplementary material: |
| 图书封面 |  |
| 描述 | Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role of epigenetic deregulation of microRNAs (miRNAs) and their target mRNAs along with epigenetic deregulation of mRNAs. This book also illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in modulating the epigenetic reprogramming of miRNAs and mRNAs for the prevention and/or treatment of human malignancies. It is well known that genetic aberrations, especially inherited through parents (somatic genetic alterations) contribute to the development of less than 10% of all cancer yet epigenetic alterations in genes especially through selective methylation and acetylation appears to be responsible for the development and progression of the vast majority of all cancers. Therefore, understanding the role of epigenetics in the regulation of genes especially through deregulated expression of miRNAs as presented in this book will allow scientists to devi |
| 出版日期 | Book 2013 |
| 关键词 | Cancer; Epigenetics; Methylation and acetylation; mRNA regulation; miRNA regulation |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-6612-9 |
| isbn_softcover | 978-94-017-8080-3 |
| isbn_ebook | 978-94-007-6612-9 |
| copyright | Springer Science+Business Media Dordrecht 2013 |
发表于 2025-3-21 16:22:02
