Titlebook: Enzyme- and Transporter-Based Drug-Drug Interactions; Progress and Future K. Sandy‘Pang ,A. David‘Rodrigues,Raimund M. Peter Book 2010 Spr

讥笑

FORGO

痛打

Extrapolation of In Vitro Metabolic and P-Glycoprotein-Mediated Transport Data to In Vivo by Modelinosed to improve the accuracy of the prediction. Also, a method to predict the alterations caused by drug–drug interactions mediated by intestinal cytochrome P450 3A4 or P-glycoprotein was introduced. In this chapter, these methods and computerized simulation method are shown.

PATRI

一起

老巫婆

inconceivable

The In Vitro Characterization of Inhibitory Drug–Drug Interactions Involving UDP-Glucuronosyltransfeat influence UGT activity in vitro have also led to the development of experimental approaches that accurately predict the magnitude of known DDIs involving glucuronidated drugs, but further work in this area is required to demonstrate the generalizability of these models.

感情脆弱

SEMI

Afrika 1991 — Das Jahr im Überblicksupplement this information. Nowadays, metabolic and transport statuses are easily accessible by genotyping and are an important prerequisite to fully judge the potential of a drug for drug interactions.

原谅