| 书目名称 | Environmental Factors, Genes, and the Development of Human Cancers | | 编辑 | Deodutta Roy,M. Tevfik Dorak | | 视频video | http://file.papertrans.cn/313/312642/312642.mp4 | | 概述 | This book addresses the effects of environment on the etiology, development and the susceptibility of human cancer..Includes supplementary material: | | 图书封面 |  | | 描述 | .Cancer is a complex disease. Only 5-10% of human cancers are hereditary in nature. Many of us think of environmental agents when we think of carcinogens. The environment includes all that surrounds us, and environmental influences include not only chemical, physical and biological toxicants, but also diet and lifestyle. In this broadest sense, the environment contributes substantially in the development of human cancer. This book will describe how environment contributes to malignant transformation leading to profound changes in the genetic and signaling networks that control the functioning of the cell. It will critically discuss the understanding of the effects of environment on the development, progression and metastasis of cancer with current knowledge of the signaling networks that support functioning of transformed human cells. Genes and environmental factors that influence the origins of cancer are not necessarily the same as those that contribute to its progression and metastasis. Susceptibility gene variants for each specific cancer are being identified with emerging evidence of gene–environment interaction. Gene-environment interactions will be discussed through each spe | | 出版日期 | Book 2010 | | 关键词 | brain tumors; cancer; carcinogenesis; cell; liver; metastasis; mutagen; ovarian cancer; research | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4419-6752-7 | | isbn_softcover | 978-1-4899-8219-3 | | isbn_ebook | 978-1-4419-6752-7 | | copyright | Springer Science+Business Media, LLC 2010 |
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