Titlebook: Environmental Epigenetics; L. Joseph Su,Tung-chin Chiang Book 2015 This is a U.S. Government work and not under copyright protection in th

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Environmental Epigenomics: Applications of Epigenetic Biomarkers to Investigate Epigenetic Alteratigenetic alterations in blood and tumor DNA. Epidemiological methods used to incorporate epigenetic alterations into studies of disease etiology as well as current methods used to apply and critically evaluate study results reporting associations between environmental exposure and disease are described.

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Interplay of Epigenetics, Genome Rearrangement, and Environment During Development,driven genome rearrangement in mammals at organismal level is still missing. It is arguable that genome rearrangement, which introduces genome diversity, is a driving force of mammalian development. There are some indirect evidence supporting that such genome rearrangement occurs at organismal level.

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https://doi.org/10.1007/978-3-642-51823-2ternal pregnancy exposures on offsprings’ breast cancer via epigenetic modifications could be carried out through multiple generations of offspring. In this chapter, we aim to summarize findings from both experimental and epidemiological studies investigating associations between maternal pregnancy exposures and offspring’s breast cancer risk.

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