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Titlebook: Environmental Endocrinology and Endocrine Disruptors; Endocrine and Endocr Rosario Pivonello,Evanthia Diamanti-Kandarakis Living reference

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发表于 2025-3-21 19:09:28 | 显示全部楼层 |阅读模式
书目名称Environmental Endocrinology and Endocrine Disruptors
副标题Endocrine and Endocr
编辑Rosario Pivonello,Evanthia Diamanti-Kandarakis
视频video
概述Provides readers with a comprehensive grasp of all aspects of environmental endocrinology.Provides evidence from preclinical and clinical studies.Provides overview of mechanisms underlying environment
丛书名称Endocrinology
图书封面Titlebook: Environmental Endocrinology and Endocrine Disruptors; Endocrine and Endocr Rosario Pivonello,Evanthia Diamanti-Kandarakis Living reference
描述This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic..
出版日期Living reference work 20200th edition
关键词endocrine axes; hormone; human health; cancer; environmental chemicals; hypogonadism; infertility
doihttps://doi.org/10.1007/978-3-030-38366-4
isbn_ebook978-3-030-38366-4
issn_series 2510-1927
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发表于 2025-3-21 21:14:11 | 显示全部楼层
Environmental Endocrinology and the Hypothalamus-Pituitary-Thyroid Axis,ose which may not be predicted at higher doses, there being a nonlinear relationship (nonmonotonic dose-response) between dose and effect. Among the various categories of EDCs that may disrupt thyroid function, some are more analytically discussed. Polychlorinated biphenyls (PCBs), which are halogen
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Environmental Impact on Bone Health,d bone formation. Highly differentiated cells and multiple hormonal and molecular pathways are involved in this remodeling process that is unavoidably affected by normal aging. Apart from aging, several factors such as geographic variation, climate conditions, nutritional status, socioeconomic statu
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Environmental Impact on Female Fertility and Pregnancy, particular concern among women of childbearing age. The rise in the above adverse reproductive health outcomes could be partly attributed to the exposure to hazardous factors ubiquitously found in the environment. To investigate this hypothesis, in this chapter, we summarize the current evidence on
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Environmental Impact on Semen Quality and Male Fertility, system may be caused by several environmental factors, including endocrine-disrupting chemicals (EDCs), heavy metals, air pollution, and electromagnetic fields. These compounds interfere with the action of hormones via multiple mechanisms and thus may lead to male infertility of both animals and hu
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Environmental Impact on Sexual Response, reproductive organs and secondary sexual characteristics, sexual function, and sexual orientation/core gender identity. Results from the studies conducted on animals provide insights into the potential mechanisms of EDCs on the sexual differentiation and function and point to the differential sensi
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Environmental Impact on the Hypothalamus-Pituitary-Testis Axis, of male gonad to external insults, starting from gestation age and during all growth phases. Three main phases are particularly susceptible for subsequent normal testis development and function: the intrauterine phase, the neonatal phase comprising the so called minipuberty, and puberty. However, e
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