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派博传思国际中心 »期刊书目

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Titlebook: Engineering and Application of Pluripotent Stem Cells; Ulrich Martin,Robert Zweigerdt,Ina Gruh Book 2018 Springer International Publishing

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发表于 2025-3-21 17:36:11 | 显示全部楼层 |阅读模式
书目名称Engineering and Application of Pluripotent Stem Cells
编辑Ulrich Martin,Robert Zweigerdt,Ina Gruh
视频video
概述Presents different bioengineering strategies applied to pluripotent stem cells.Explores the (re)programming to pluripotency.Reviews the use of pluripotent stem cells for tissue engineering and drug sc
丛书名称Advances in Biochemical Engineering/Biotechnology
图书封面Titlebook: Engineering and Application of Pluripotent Stem Cells; Ulrich Martin,Robert Zweigerdt,Ina Gruh Book 2018 Springer International Publishing
描述.​This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening..This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research..
出版日期Book 2018
关键词pluripotency; small molecules; Transgene-Free iPSCs; Genome engineering; drug screening; tissue engineeri
版次1
doihttps://doi.org/10.1007/978-3-319-73591-7
isbn_softcover978-3-030-08817-0
isbn_ebook978-3-319-73591-7Series ISSN 0724-6145 Series E-ISSN 1616-8542
issn_series 0724-6145
copyrightSpringer International Publishing AG 2018
The information of publication is updating

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Scalable Cardiac Differentiation of Pluripotent Stem Cells Using Specific Growth Factors and Small pproaches will require efficient and highly reproducible processes for the mass production of well-characterized CM batches..On their way toward beating CMs, hPSCs initially undergo an epithelial-to-mesenchymal transition into a primitive-streak (PS)-like population that later gives rise to all endo
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Targeted Gene Editing in Human Pluripotent Stem Cells Using Site-Specific Nucleases,ative therapies and biomedical research. With the advancement of ZFNs, TALENs, and the CRISPR/Cas9 technology, straightforward and precise manipulation of the genome of human pluripotent stem cells (PSC) became possible, allowing relatively easy and fast generation of gene knockouts, integration of
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Acquired Genetic and Epigenetic Variation in Human Pluripotent Stem Cells, selective growth advantage in culture. Additionally, there is evidence that reprogramming of human induced pluripotent stem cells (hiPSCs) introduces mutations. This poses a challenge to both the safety of clinical applications and the reliability of basic research using hPSCs carrying genomic vari
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Requirements for Using iPSC-Based Cell Models for Assay Development in Drug Discovery,in vitro systems are being developed to overcome some of these challenges. In particular, induced pluripotent stem cells (iPSCs) have provided the opportunity to generate human cell types that can be utilized for developing more disease-relevant cellular assay models. As the use of these complex mod
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https://doi.org/10.1007/978-3-319-73591-7pluripotency; small molecules; Transgene-Free iPSCs; Genome engineering; drug screening; tissue engineeri
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