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Titlebook: Endotoxin; Herman Friedman,T. W. Klein,Alois Nowotny Book 1990 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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Immunochemistry of Lipid Aspecific and common or cross-reactive epitopes, in which the specificities are derived from the chemical and conformational structures of the backbone and/or acyl groups. In these studies, the in vitro antigenic reactivity of a number of chemically synthesized lipid A analogs with free lipid A prepa
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Bacterial Lipopolysaccharides: Relationship of Structure and Conformation to Endotoxic Activity, Serificance for bacterial viability and the interaction of bacteria with host organisms. Together with phospholipids and proteins, lipopolysaccharides form the outer membrane of gram-negative bacteria. This outer membrane has an asymmetric architecture, i.e., lipopolysaccharides are located exclusively
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Structure-Activity Relationship of Chemically Synthesized Nonreducing Parts of Lipid a Analogsomplicated chemical complexes of enormous molecular weight. The lipopolysaccharide-protein complex which proved to exhibit all the activities of endotoxin was first isolated from the cell wall of gram-negative bacteria. After precise immunochemical studies on endotoxin by several pioneers, the porti
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The Structure of O-Specific Polysaccharide of , 019 Lipopolysaccharidesification) allowed us to divide the investigated LPS’s into 16 chemotypes. The major part of LPS’s is clustered in two chemotypes — IX and XV (4). The structure of the 0 specific part of LPS, isolated from . serotype 019 strain, from the chemotype IX, together with some serological data, is present
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Cloning and Expression of , GeneLPS) from . 08, 09, ., and other members of the family Enterobacteriaceae (1, 2, 3, 6). The gene . is located close to . genes at 84.5 min on the . chromosomal map in the gene order . (4). In the recent study, it was suggested that the products of the . gene(s) function mainly in supporting the coor
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