Titlebook: Endothelin; Molecular Biology, P Robert F. Highsmith Book 1998 Springer Science+Business Media New York 1998 cardiovascular.endothelium.enz

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书目名称Endothelin影响因子(影响力)




书目名称Endothelin影响因子(影响力)学科排名




书目名称Endothelin网络公开度




书目名称Endothelin网络公开度学科排名




书目名称Endothelin被引频次




书目名称Endothelin被引频次学科排名




书目名称Endothelin年度引用




书目名称Endothelin年度引用学科排名




书目名称Endothelin读者反馈




书目名称Endothelin读者反馈学科排名

破裂

Molecular Biology of the Endothelin Receptors,ion of the molecular details of the endothelin (ET) system has progressed rapidly via a multidisciplinary approach using the tools of biochemistry, chemistry, pharmacology, and molecular biology. Milestones in the development of this area include the isolation . and three-dimensional structure deter

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Molecular Biology of Endothelin-Converting Enzyme (ECE),onsisting of 21 amino-acid residues, is generated from an inactive form of big ET-1 by a specific enzyme, called endothelin-converting enzyme (ECE). Accelerated production of ET-1 in damaged vascular endothelial cells was strongly suggested to be involved in the development of various fatal cardiova

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Endothelin Receptor-Signaling Mechanisms in Vascular Smooth Muscle,most lining of all blood vessels. By virtue of its location at the blood—tissue interface in vivo, vascular endothelium is ideally suited to play a pivotal role in vascular tone regulation. It is now well-documented that endothelial cells produce several vasoactive substances that activate or inhibi

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是贪求

The Renal and Systemic Hemodynamic Actions of Endothelin,elial cell constricting factor (EDCF) by Hickey et al. in 1985 . and the subsequent cloning of endothelin-1 (ET-1) by Yanagisawa et al., in 1988 .. Endothelin and endothelinrelated peptides (ET-1, ET-2, and ET-3) have profound effects on a number of hemodynamic variables relating to cardiovascular a

是贪求

The Development of Specific Endothelin-Receptor Antagonists,em, where they are potent vasoconstrictors and pressor agents, although there may also be accompanying vasodilatation, particularly at low concentrations .,.. The ETs also have numerous other effects, such as stimulating the release of autacoids and hormones, contracting nonvascular smooth muscle, p

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European Values in the New Global Contextses that transduce signals from cell surface receptors to the nucleus, thus altering the transcription of genes which lead to the mitogenic response. In this chapter I will first explore the role of the ETs as growth factors and discuss candidate modulators or transducers of the mitogenic signal. Th

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