Titlebook: Endothelin; Gabor M. Rubanyi Book 1992 American Physiological Society 1992 Endothelin.biology.cardiovascular.cardiovascular system.central

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Bernstein-test

Cellular Actions of Endothelin in Vascular Smooth Muscle,endothelia is a potent stimulator of both vascular and nonvascular smooth muscle contraction.. It is now recognized that the human endothelin “family” contains three distinct isoforms (endothelin-1, endothelin-2, and endothelin-3) that are products of three separate genes..

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Inordinate

Endothelin in Human Disease. I: Essential Hypertension, Vasospastic Angina, Acute Myocardial Infarc water, electrolytes, and blood pressure, such as atrial natriuretic peptide,. aldosterone,. and renin.. Experimental results indicate that endothelin-1 is involved in the control of cardiovascular homeostasis and in the pathophysiology of cardiovascular disorders (see Chapter 16).

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Endothelium-Derived Contracting Factors,1.1), which are explained best by the production of mediators that activate the underlying vascular smooth muscle. By analogy with endothelium-derived relaxing factor,. the endothelial substances leading to rapid increases in tension have been termed “endothelium-derived contracting factor(s)” (EDCF)..

FORGO

Hypothetical Role of Endothelin in the Control of the Cardiovascular System, was termed “endothelium-derived relaxing factor” (EDRF).. Subsequent studies have shown that the major EDRF is nitric oxide or a labile nitroso compound. formed from L-arginine in the endothelial ce11..

Ancestor

Schulungsprogramm Gefahrguttransportmologous to sarafotoxin S6b, a venom peptide isolated from an Israeli asp, ... In our brief summary of present knowledge of the cellular synthesis of this new peptide family, we emphasize the gene structure, regulation of gene expression, and biosynthesis of mature endothelin.

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Allgemeine Gefahreigenschaften,identified.. In addition, attention has been directed to their possible involvement in a variety of pathological conditions, including asthma, vasospasm, hypertension, renal failure, and myocardial infarction..

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