Titlebook: Endogenous Stem Cell-Based Brain Remodeling in Mammals; Marie-Pierre Junier,Steven G. Kernie Book 2014 Springer Science+Business Media New

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Introduction,ry real potential of cell-based therapies as a compelling choice for regenerative medicine. In the central nervous system, where cellular specialization is so diverse, this mode of therapy is particularly attractive. However, as more is becoming known about the intrinsic repair capabilities of the b

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Structural Plasticity in Adult Nervous System: An Historic Perspective,uscule changes of their axonal terminal branches and synaptic boutons, simultaneously with the growing and pruning of their distal dendritic branches and spines. In this review, we summarize the history of the concept of structural plasticity from its beginnings in the nineteenth century to its cons

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Role of Neural Stem and Progenitor Cells in the Adaptation of the Brain to Injury,ury remains largely unknown. In addition, glial-specific progenitors appear to be quite widespread throughout the brain, and their roles in injury-induced remodeling are also just beginning to emerge. Ongoing adult neurogenesis occurs in two regions of the mammalian brain—the subventricular zone (SV

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Role of Adult Neurogenesis in Seizure-Induced Hippocampal Remodeling and Epilepsy,seizure-induced plasticity, and the pathogenesis of epilepsy is complex and not well understood, but there is great interest in the therapeutic potential of modulating the effects of seizures on dentate granule cell (DGC) neurogenesis. In this chapter, we discuss how seizure activity or epileptic in

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Neurogenesis and Gliogenesis in the Postnatal Hypothalamus: A New Level of Plasticity for the Regulch new neurons and glial cells differentiate from neural stem/progenitor cells and functionally integrate into existing cellular networks and contribute to their functions. Besides the two well-established neurogenic areas of the mammalian brain, the subventricular zone of the lateral ventricles and