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Titlebook: Endocrine Disruptors Part I; M. Metzler Book 2001 Springer-Verlag Berlin Heidelberg 2001 Endokrinologie.Hormone.U.biphenyls.endocrine disr

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楼主: dabble
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Antiandrogenic Effects of Environmental Endocrine Disruptors,een characterized and yielded insight into the development of in vitro and in vivo screening assays to detect chemicals with antiandrogen activity. These mechanisms and efforts to develop screening assays are discussed in the context of current endocrine disruptor screening and testing strategies.
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Chemistry of Natural and Anthropogenic Endocrine Active Compounds,emicals, and their chemical structures are surprisingly diverse. This chapter provides an overview of the chemical structures of typical endocrine active compounds, which are discussed in other chapters of this book with respect to their occurrence, mechanisms of action, implications for human health, and environmental significance.
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In Vitro Methods for Characterizing Chemical Interactions with Steroid Hormone Receptors,valuate endocrine-disrupting properties of chemical substances and common mixtures. The program will evaluate tens of thousands of compounds and as a result assays will need to be developed that will allow for the screening of a large number of chemicals. This chapter describes several in vitro assa
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Exposure to Endogenous Estrogens During Lifetime,E2), and estriol (E3) during the different phases of life in the human female and male. During fetal life, E3 is the most abundant estrogen produced by the fetoplacental unit. E3 affects cerbral development, leads to breast gland swelling in both girls and boys and promotes uterine growth up to a si
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Dietary Estrogens of Plant and Fungal Origin: Occurrence and Exposure, Lignans, isoflavones, and coumestans are the three major classes of phytoestrogens to which humans and animals are exposed. Animals may be exposed to high levels of phytoestrogens while grazing in pastures or consuming feed rich in clover of alfalfa. Domestic livestock may be exposed to mycoestroge
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Hydroxylated polychlorinated Biphenyls (PCBs) and Organochlorine Pesticides as Potential Endocrine ree has been some concernregarding their potential adverse effects as endocrine-active agents. Initial studies showed that two synthetic compounds, 2′,4′,6′-trichloro- and 2′,3′,4′,5′-tetrachloro-4-biphenylol (HO-PCB3 and HO-PCB4, respectively), bound to the estrogen receptor (ER) and exhibited estr
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