Titlebook: Endocannabinoids and Lipid Mediators in Brain Functions; Miriam Melis Book 2017 Springer International Publishing AG 2017 Endocannabinoids

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Endocannabinoids and Lipid Mediators in Brain Functions978-3-319-57371-7

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use ofcannabinoids and/or drugs regulating endocannabinoid levels in vivo as therapeutic target(s) in neurological and neuropsychiatric disorders. In this book new findings and ideas about the endocannabinoid 978-3-319-86145-6978-3-319-57371-7

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Endocannabinoids, Stress, and Negative Affect,sure to a stressor. With respect to this response, preclinical research demonstrates that the endogenous cannabinoid (ECB) system constrains the hypothalamic-pituitary-adrenal axis and plays a major role in the habituation to stressors. Specifically, anandamide tonically constrains activation of str

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Cell-Autonomous Endocannabinoid Production Shapes Polarized and Dynamic Distribution and Signaling ucture, conformation, and function of cell-membrane-embedded proteins, such as G-protein-coupled receptors (GPCRs). The type-1 cannabinoid receptor CB., because of a relatively unstable GPCR structure and specific entry sites for lipids diffusing from the plasma membrane, may be particularly sensiti