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Titlebook: Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders; Elisabeth J. Van Bockstaele Book 2013 Springer Science

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书目名称Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders
编辑Elisabeth J. Van Bockstaele
视频video
概述Content written by the leading experts in the field.Presents potential therapeutic applications.Most up-to-date information available
图书封面Titlebook: Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders;  Elisabeth J. Van Bockstaele Book 2013 Springer Science
描述The past decade has seen tremendous growth in the study of cannabinoid receptor signaling in brain.  The impact and consequences of cannabinoid modulation of monoaminergic (dopamine, norepinephrine, and serotonin) circuits is becoming more clear.  Scientists have shown significant interaction between these two systems in a variety of psychiatric and neurological disorders such as affective disorders, multiple sclerosis, and pain or pain disorders.  The overarching goal of .Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders. is to provide current information on advances in the field of endocannabinoid signaling and potential therapeutic applications with a particular emphasis on monoaminergic circuits.  ​
出版日期Book 2013
关键词cannabinoid receptors; cannabinoid therapy for neurological disorders; cannabinoid therapy for psychia
版次1
doihttps://doi.org/10.1007/978-1-4614-7940-6
isbn_softcover978-1-4899-9608-4
isbn_ebook978-1-4614-7940-6
copyrightSpringer Science+Business Media New York 2013
The information of publication is updating

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Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders978-1-4614-7940-6
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Gender Disparity of Depression: The Role of Endocannabinoids and Noradrenergic Function,response being a major area of interaction. Norepinephrine acts as a “gatekeeper” to the body’s stress response, mobilizing the HPA axis to react to stressors. The endocannabinoid system is also a “gatekeeper” to this response, preventing maladaptive HPA hyperactivation and potentially protecting th
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Cannabinoids, Monoamines, COMT and Schizophrenia: Pathobiological Mechanisms in Psychosis,as shown showing that variation in the genes implicated in dopamine neurotransmission (COMT, AKT1, D2R) moderates the psychotomimetic effects of cannabis exposure. Further studies are required to clarify the molecular underpinnings of dopamine system involvement in cannabis-induced psychosis.
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Structuring the Knowledge Management System, Allosteric modulation of cannabinoid receptors may usher in new classes of medicinal compounds capable of enhancing signals generated by endocannabinoids. Natural polymorphisms and alternative splice variants may also contribute to the pharmacological diversity of the cannabinoid receptors. Thus, e
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