| 书目名称 | Electron Microscopy of Axon Degeneration: A Valuable Tool in Experimental Neuroanatomy |
| 编辑 | John F. Alksne,Theodor W. Blackstad,Lowell E. Whit |
| 视频video | |
| 丛书名称 | Advances in Anatomy, Embryology and Cell Biology |
| 图书封面 |  |
| 描述 | Experimental methods for the mapping of nervous pathways are based partlyon the study of retrograde processes in the perikaryon, partlyon the demonstration of degenerative processes along the peripheral part of a transected axon. For this purpose, the Marchi method by which a selective staining of degenerating myelin is obtained has been extensively used. However, when this method is used the non-myelinated terminals of the transected axons are not stained. The introduction, about two decades ago, of silver impregnation as a means of tracing degenerating axons (especially the Glees and Nauta methods) by which also terminal boutons can be demonstrated, led therefore to revolutionary progress in the investigation of interneuronal connections. Notwithstanding, there are weH known difficulties involved in this kind of research. The capriciousness of the silver methods not seldom results in failure of impregnation with loss of valuable experimental animals. But even when well impregnated sections are used, other fundamental difficulties exist. One of the major problems is to prove beyond doubt that the impregnated structures are degenerating boutons and not merely fragments of non-termi |
| 出版日期 | Conference proceedings 1966 |
| 关键词 | Axon; anatomy; animals; electron microscopy; microscopy; myelin; neuroanatomy |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-662-30450-1 |
| isbn_ebook | 978-3-662-30450-1Series ISSN 0301-5556 Series E-ISSN 2192-7065 |
| issn_series | 0301-5556 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
发表于 2025-3-21 18:35:07
