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Titlebook: Electromechanobiology of Cartilage and Osteoarthritis; A Tribute to Alan Gr Brianne K. Connizzo,Lin Han,Robert L. Sah Book‘‘‘‘‘‘‘‘ 2023 The

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Hip Osteoarthritis: Bench to Bedside Perspectiveip osteoarthritis and the role that structural abnormalities may play as a causative factor. Recent advances in open and minimally invasive techniques such as the periacetabular osteotomy, surgical hip dislocation and arthroscopic approaches have allowed us safe access into the joint to not only imp
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https://doi.org/10.1057/9780230613157rush”-like ultrastructure of aggrecan was directly visualized for the first time. Meanwhile, molecular mechanics of aggrecan was studied using a physiological-like 2D biomimetic assembly of aggrecan on multiple fronts, including compression, dynamic loading, shear, and adhesion. These studies not on
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https://doi.org/10.1057/9780230360143uctural reliability analysis. That is, causal, deterministic models placed in the framework of the probabilistic approach of structural reliability analysis could be used to understand, predict, and mitigate the risk of cartilage failure or pathology. At the heart of this approach is seeing cartilag
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Kai Maaz,Frauke Kreuter,Rainer Watermanns has proved more difficult, because the dense, anionic, extra-cellular matrix of cartilage limits access to the chondrocytes embedded within it. As Grodzinsky and colleagues have shown, the matrix imposes strict limits on the size and charge of particles able to diffuse through the entire depth of
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The Men Hemmed in with the Spears,n understanding the proinflammatory response to injury and in developing effective therapies that are based on an in-depth understanding of complex structure-function relationships that underlay articular cartilage function and degeneration.
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