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Titlebook: Eicosanoids, Lipid Peroxidation and Cancer; Santosh K. Nigam,David C. H. McBrien,Trevor F. Sla Book 1988 Springer-Verlag Berlin Heidelberg

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Diene Conjugation and Peroxidation in Precancer-radical mediated breakdown of lipids became synonymous with peroxidation. This is particularly true today in areas of biomédical research: indeed, it finds expression in the title of the present Symposium. It can no longer be supported or justified by experimental evidence. Second, in medicine, lip
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Tumour Promoters and Prostaglandin Production years, Samuelsson and his colleagues have done much to describe the biochemical pathways for the biosynthesis and metabolism of the arachidonic acid metabolic products (Samuelsson 1976, 1985; Hamberg and Samuelsson 1974).
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Eicosanoid Regulation of Macrophage In Vitro Cytostatic Function Towards Tumour Cellsple macrophage lysosomal enzyme secretion is stimulated by the 5-lipoxygenase product leukotriene (LT)C. and inhibited by the cyclo-oxagenase metabolic Prostaglandin (PG)E.. Further, the stimulatory action of LTC. is enhanced by inhibitors of cyclo-oxygenase (Schenkelaars anf Bonta 1986). Also the d
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The Role of Platelet-Activating Factor and Structurally Related Alkyl Phospholipids in Immune and Cyety. This ether linkage confers unique pharmacological properties upon this group of compounds and distinguishes them from other phospholipids which usually possess an ester linkage at this position. Alkyl phospholipids are now known to be more abundant in various cell types than previously thought
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Interaction of Macrophages and Mast Cells in the Production of Prostaglandins and Leukotrienesdefence by phagocytosis, cytotoxic activity and immune regulation (Allison et al. 1978; Nathan et al. 1980). Mast cells are best characterized for their role in immediate hypersensitivity reactions. However, they also have other functions in host defence. They have been shown to phagocytose, though
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