| 书目名称 | Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis | | 编辑 | Claude L. Malmendier,Petar Alaupovic | | 视频video | | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | Plasma lipoproteins constitute a unique macromolecular system of lipid-protein complexes responsible for the transport of lipids from their sites of origin to their sites of utilization either as metabolic fuel or as structural components of cell membranes. Although studies on the role of lipoproteins in the mechanism of lipid transport are meritorious in their own right, the ever-increasing interest in chemical and functional properties of this remarkable class of conjugated proteins stems from the impressive evidence of their direct involvement in the genesis and develop ment of atherosclerotic lesions. The initial emphasis on neutral lipids and phospholipids as the most characteristic constituents of operationally defined lipoprotein classes has shifted in recent years to their protein moieties or apolipoproteins. The discovery of a number of apolipoproteins and characterization of familial hypolipoproteinemias as apolipoprotein deficiency disorders indicated that apolipoproteins play an essential role in maintaining the structural stability and integrity of lipoprotein particles. In addition to their role in the formation of lipoproteins, apolipoproteins were shown to perform | | 出版日期 | Book 1988 | | 关键词 | Lipoprotein; atherosclerosis; cytokine; genetics; heart; high-density lipoprotein (HDL); protein; protein c | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4613-0733-4 | | isbn_softcover | 978-1-4612-8055-2 | | isbn_ebook | 978-1-4613-0733-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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发表于 2025-3-21 16:21:55
