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Titlebook: Effects of Nicotine on Biological Systems; Franz Adlkofer (Professor of Medicine, Scientific Book 1991 Springer Basel AG 1991 Alzheimer´s

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楼主: ATE
发表于 2025-3-30 10:20:10 | 显示全部楼层
Ioannis Gkioulekas,Lazaros G. Papageorgiouin the amounts of material retained by the column. The above results account for higher cotinine values than have been observed in urine when levels are compared to gas chromatography measurements and help account for the recovery of a higher proportion of metabolized nicotine.
发表于 2025-3-30 14:51:26 | 显示全部楼层
https://doi.org/10.1007/978-0-387-21528-0liver. NNN was not genotoxic in the liver up to 100 mg /kg, and the compound was only moderately positive in doses up to 500 mg/kg. No genotoxicity was observed in testes, or thymus by either compound. First results with a single cell analysis of DNA damage by . nick translation indicate both the compounds to be genotoxic in esophageal cells.
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Toxicokinetics of Nicotine-Derived Nitrosamines in the Ratliver. NNN was not genotoxic in the liver up to 100 mg /kg, and the compound was only moderately positive in doses up to 500 mg/kg. No genotoxicity was observed in testes, or thymus by either compound. First results with a single cell analysis of DNA damage by . nick translation indicate both the compounds to be genotoxic in esophageal cells.
发表于 2025-3-31 01:55:01 | 显示全部楼层
K. Mohaideen Abdul Kadhar,G. Anandm levels. After smoking nicotine values in pooled saliva from the parotid gland were about 10 times higher than those in serum. Cotinine values in saliva are slightly higher than those in serum, but the differences are marginal. TSNA could neither be detected after nicotine infusion nor after smoking.
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发表于 2025-3-31 15:52:22 | 显示全部楼层
Relevance of Nicotine-Derived N-Nitrosamines in Tobacco Carcino-Genesisated cancer are discussed, as is the need for developing methods for the reduction of TSNA in tobacco and tobacco smoke. Future research should concentrate on biomarkers for the exposure of tobacco users to TSNA, the DNA binding of TSNA in humans, and on the question of endogenous formation of TSNA.
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