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Titlebook: Effects of Drugs on Cellular Control Mechanisms; B. R. Rabin,R. B. Freedman Textbook 1971Latest edition Macmillan Publishers Limited 1971

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Cyclic 3′, 5′-Adenosine Monophosphate and the Anaphylactic ReactionThe anaphylactic reaction (immediate-type allergy) is the reaction mediated by certain classes of antibodies known collectively as anaphylactic (tissue-sensitising) antibodies. Various species produce their own characteristic anaphylactic antibodies [1, 2, 3].
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https://doi.org/10.1007/978-1-349-01321-0control; control mechanism; drugs; mechanism
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Macmillan Publishers Limited 1971
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Effect of 3′, 5′-Cyclic Amp on Gene Expression in Symposium have been reminding us, a number of effects are exerted independent of the transcription process, presumably by activating latent enzymatic machinery-or possibly latent messenger RNA. In contrast, for the best characterized systems in bacteria, cyclic AMP helps to determine the repertoire of gene transcription open to the cell [1–5].
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Interaction of Prostaglandins and Cyclic Ampent of major significance to the biomedical community. It is against this background that one must view the discovery of prostaglandins by von Euler [1], Goldblatt [2], and Bergstrom and Sjövall [3]. The promise of these substances in therapeutics is already great [4], but perhaps greater is their significance in cell biology.
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‘Pleiotypic’ and ‘Specific’ Hormonal Control of Gene Expression in Mammalian Cells to as the ‘pleiotypic’ [1] and ‘specific’ modes of regulation. The pleiotypic control system refers to a coordinated set of reactions which respond in a characteristic way when cellular growth is stimulated by a specific hormone. Some of the reactions under this type of general control are:.Respons
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Control of Oestrogen Action by Specific Oestrogen-Protein Interactionn rat kidney (Table 1). At the pharmacological level, they have been used for the treatment of prostatic cancer [7] and the induction of kidney tumours [6]. Any explanation of how oestrogens exert their biological effects must answer two basic questions. How can a relatively simple molecule like oes
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The Effects of Steroid Hormones and Carcinogens on the Interaction of Membranes with Polysomesn messenger RNA molecules into amino-acid sequences of proteins [1]. Ribosomes are frequently found in the cell in the form of aggregates called polysomes. The ribosomes in a polysome are believed to be attached to a single messenger RNA molecule and simultaneously to translate the encoded informati
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The Effects of Drugs and Steroid Hormones on the Enzymes of the Endoplasmic Reticulumg. glucose-6-phosphatase and glucuronyl transferase, and with protein synthesis. This subcellular structure is, however, more widely associated with the activities of the mixed function oxidases, enzyme(s) requiring reduced nicotinamide adenine dinucleotide phosphate (NADPH.) and molecular oxygen fo
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