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Titlebook: Early Markers in Parkinson’s and Alzheimer’s Diseases; Philippe Dostert,Peter Riederer,Romeo Roncucci Book 1990 Springer-Verlag/Wien 1990

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978-3-7091-9100-2Springer-Verlag/Wien 1990
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IntroductionI am very grateful for having been invited to this meeting. Even though I have not been personally working on Parkinson’s disease, I am obviously very interested in the study of degenerative diseases, in particular of Alzheimer’s disease, in the treatment of which there is some hope that the Nerve Growth Factor (NGF) may be of use.
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Contribution of motor performance tests to the early diagnosis of Parkinson’s diseasees of the disease and standardized motor performance tests can contribute to its detection. Since we established that a deterioration of the test results is highly age-correlated for these patients, we expect that follow-up testing will further contribute to improve selectivity.
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https://doi.org/10.1007/978-981-19-1219-1nflexibility as frequent premorbid personality features of parkinsonians. Neurobehavioural abnormalities found in the early stages of the disease include set-shifting difficulties, cognitive slowing and depression. Premorbid behavioural traits might represent the earliest sign of brain neurochemical dysfunction in Parkinson’s disease.
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https://doi.org/10.1007/978-3-662-50533-5rally unimpaired. In other neurodegenerative conditions accompanied by parkinsonism both “pre” and “post-synaptic” binding of tracers seems to be impaired..In PD the loss of cells within the nigrostriatal pathway seems less outspoken when compared to the severe decrease of endogenous dopamine concentration.
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