| 书目名称 | Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives | | 编辑 | Mohammed Tarique | | 视频video | | | 概述 | Reviews novel molecular targets for antimalarial drug development.Explores metabolic enzymes as druggable targets against malaria.Examines Plasmodium Kinases as potential drug targets for malaria | | 图书封面 |  | | 描述 | .This book offers a comprehensive exploration of malaria, a life-threatening disease affecting millions globally, with a focus on the parasitic organisms of the genus Plasmodium that cause it. It discusses the challenges posed by the disease, especially in economically developing regions, and delves into the biology and pathophysiology of the Plasmodium species, including their genetic flexibility and resistance to treatments. Special attention is given to P. falciparum, the most dangerous of these parasites, detailing its complex life cycle, interaction with human hosts, and the severe clinical manifestations it can induce. The book further explores the global health concern of antimalarial drug resistance, highlighting the WHO‘s efforts in combating the disease and the necessity for novel treatments. Innovative research directions, such as targeting the unique organelles of Plasmodium like the apicoplast and employing proteasome inhibitors, are thoroughly examined as potential strategies in the development of new antimalarial drugs. Additionally, it addresses the critical role of the hemoglobin digestion process in the parasite‘s lifecycle, presenting it as a promising target for | | 出版日期 | Book 2024 | | 关键词 | Malaria; Plasmodium falciparum; Drug targets; Protein kinases; Tranporter inhibitors | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-19-4484-0 | | isbn_softcover | 978-981-19-4486-4 | | isbn_ebook | 978-981-19-4484-0 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
The information of publication is updating
|
|
发表于 2025-3-21 17:14:08
