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Titlebook: Drug Design and Discovery; Inhibitors of Mitoge Surya K. De Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive lice

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发表于 2025-3-21 18:03:54 | 显示全部楼层 |阅读模式
书目名称Drug Design and Discovery
副标题Inhibitors of Mitoge
编辑Surya K. De
视频video
概述Describes role of small molecules in the modulation of MAPK pathways in the development of future medicine therapies.Analyzes recent challenges in designing small molecule inhibitors of MAP kinases.Pr
图书封面Titlebook: Drug Design and Discovery; Inhibitors of Mitoge Surya K. De Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive lice
描述.This book covers the important role small molecules can play in the modulation of stress-activated protein kinase (SAPK), also called the mitogen-activated protein kinase (MAPK) pathway, and the potential this may offer in enabling the development of future medicine therapies. It is clear that MAP kinase pathway therapies could continue to drive increasing interest in the field, both within academic laboratories and also in the biotechnology and pharmaceutical sectors. This book provides an overview of protein kinase inhibitors, the biological roles of MAP kinases, ATP-competitive and non-competitive inhibitors, covalent inhibitors, and more. This book is intended for professors in academia, researchers in pharmaceutical and biotechnology sectors working on protein kinases, and graduate students in pharmacy/chemistry..
出版日期Book 2024
关键词Protein Kinase Inhibitors; Drug Design; Drug Delivery; Mitogen-Activated Protein Kinase Inhibitors; Clin
版次1
doihttps://doi.org/10.1007/978-3-031-75682-5
isbn_softcover978-3-031-75684-9
isbn_ebook978-3-031-75682-5
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Nathan B. Fountain,Fritz E. Dreifuss are in the market for the treatment of cancer and other diseases. Many research institutes discovered preclinical ATP-competitive inhibitors of MAP kinases using fragment-based drug design or optimization of their initial hit from high-throughput screening to improve in vitro potency only but lack
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Excursus I: Values and Human Rights, specific target protein and effectively disrupt the activity of the target protein, which involve disease processes such as cancer progression, inflammatory responses, or infectious diseases. The reaction mechanisms of some FDA-approved covalent inhibitors are depicted. The binding mode of covalent
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https://doi.org/10.1007/978-3-031-75682-5Protein Kinase Inhibitors; Drug Design; Drug Delivery; Mitogen-Activated Protein Kinase Inhibitors; Clin
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