书目名称 | Dupuytren’s Disease | 副标题 | Pathobiochemistry an | 编辑 | Alfred Berger,Axel Delbrück,Rolf Hinzmann | 视频video | | 图书封面 |  | 描述 | In this volume a distinguished group of internationallyrenowned clinicians and basic researchers discuss thepresent state of knowledge of the etiologyand pathogenesisof Dupuytren‘s contracture, a disease responsible foraconsiderable portion of disabilities within the workingpopulation allover the world. Although the riddle of howthe contracture of the palmarfascia develops is stillunsolved, the data on the pathobiochemistry andclinic ofDupuytren‘s Disease achieved in recent years has led to abetter understanding of the biochemical and morphologicalprocesses underlying the deformation and malfunction of theafflicted tissues.Research in Dupuytren‘s Disease nowenters the era of molecular medicine, which opens up newexperimental means of studying the pathologicalchangeswhich occur during the formation of the contracture onamolecular level. In particular, data are presented as to therole ofspecific biological macromolecules influencing thephenotype expression ofthe palmar fascia cells which areinvolved in autoimmune reactions andpresent both at thecell surface as well as in the extracellular matrix toregulate cell-to-cell and cell-to-matrix interactions. Invitro cell culture models to i | 出版日期 | Conference proceedings 1994 | 关键词 | Aetiology; Cellular Biology; Dupuytren‘s Disease; Extrazelluläre Matrix; Histopathologie; Histopathology; | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-78517-7 | isbn_softcover | 978-3-540-57239-8 | isbn_ebook | 978-3-642-78517-7 | copyright | Springer-Verlag Berlin Heidelberg 1994 |
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