Titlebook: Drugs of Abuse, Immunomodulation, and Aids; Herman Friedman,John J. Madden,Thomas W. Klein Book 1998 The Editor(s) (if applicable) and The

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Opiate Effects on , Human Retroviral Infection,he potential effects of opiates on these retroviruses are important because of the higher incidence of infection in IDUs. Because IDUs compose one of the emerging high risk populations for infection with HIV-1 and more recently HTLV, it is relevant to analyze the direct and indirect effects of opioi

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Changes in Kappa Opioid Receptor Expression During Maturation of Mouse Lymphocytes,ing have been successful in demonstrating k opioid receptor expression on mouse immune cells.. This sensitive method employs amplification of labeling by aκ-selective opioid, fluorescein-conjugated arylacetamide (FITC-AA), with the addition of biotinylated anti-fluorescein IgG and extravidin-R-phyco

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Morphine During Pregnancy in the Rat,others (8). Since many children in our society are born to mothers addicted to morphine or heroin, or who are on methadone therapy, it could prove clinically useful to explore how immunity is altered by early exposure to opiates. To address this question, we examined cellular immune parameters in th

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Models of Linear Viscoelasticityoxicity activity (9, 10) antibody and serum hemolysin formation (11) and the phago- cytic and killing properties of peripheral blood mononuclear leukocytes (6) are all attenu- ated after . chronic morphine exposure. While the mechanisms responsible for morphine induced changes in the immune system a