Titlebook: Drugs of Abuse; Leslie L. Iversen,Susan D. Iversen,Solomon H. Snyd Book 1978 Springer Science+Business Media New York 1978 brain.chemistry

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Analgesics and their Antagonists: Structure-Activity Relationships,mist only slight ability to predict, ., the analgesic potencies of compounds. The discovery of new types of analgesics by the medicinal chemist has often been serendipitous (Eddy and May, 1973). Other new analgesics were designed through clever rationalizations based on natural products or previousl

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Sedative-Hypnotics: Animal Pharmacology,determined largely by pharmacokinetic factors. Thus, volatile anesthetics are not used as sedative-hypnotics because of difficulties with administration and short duration of action, and the sedative-hypnotics, although anesthetics in higher doses, are not routinely used as anesthetics in humans, ex

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Alcohol and Human Behavior,un to yield to empirical observations, and a clearer impression of some behavioral effects of alcohol has begun to emerge. However, the transition from mythology to an accurate descriptive phenomenology is still incomplete, and the neural mechanisms underlying the effects of alcohol are unknown. We

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Cannabis: Structure-Activity Relationships,China in 2737 . Its use as an intoxicant spread to India and North Africa and from there to Europe, probably as a result of the expedition of Napoleon during his Egyptian campaign around 1800. In the Western Hemisphere marihuana has been known for centuries in South and Central America, but it was n

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Marihuana: Human Effects, gradually disappear. Although dose administered and individual differences in personality, expectations, setting, and past drug experience all contribute to varied consequences from a given dose of cannabis, the variability in acute effects from cannabis seems no greater than with any other psychoa

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