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Titlebook: Drugs of Abuse; Neurological Reviews John Q. Wang Book 2003 Humana Press 2003

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Effects of Psychomotor Stimulants on Glutamate Receptor Expression drug-seeking behavior in addiction, including sensitization of incentive-motivational effects of drugs, enhanced ability of drug-conditioned stimuli to control behavior, and loss of inhibitory control mechanisms that normally govern reward-seeking behavior (.,.).
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Learning and Memory Mechanisms Involved in Compulsive Drug Use and Relapseus review (.) by elaborating on some particular forms of associative learning that may be central to drug addiction, although limitations of space prevent a full consideration of the many roles that learning has been suggested to play in drug addiction (.–.).
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Hybridization with Isotopic Riboprobes for Detection of Striatal Neuropeptide mRNA Expression Aftetion of distinct dopamine receptor subtypes (D.–D.) that are differentially expressed within distinct striatal neuronal populations. The predominant striatal cells are medium spiny projection neurons (70–80%) and medium aspiny interneurons (20–25%) that all contain the inhibitory neurotransmitter γ-
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Semiquantitative Real-Time PCR for Analysis of mRNA Levelsue is that if one has access to a real-time PCR thermocycler and is interested in comparing . mRNA levels, the experiments are neither difficult nor expensive to perform. Indeed, attempts to be absolutely quantitative provide a very significant set of technical concerns (.) that are not the subject
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Book 2003 the striatum have been investigated in response to drug administration. Altered expression of given mRNAs and their product proteins constitutes essential molecular steps in the development of neuroplasticity related to long-term addictive properties of drugs of abuse. With the multiple labeling me
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