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Titlebook: Drugs in Breast Milk; John T. Wilson Book 1981 ADIS Press 1981 research

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发表于 2025-3-21 19:12:57 | 显示全部楼层 |阅读模式
书目名称Drugs in Breast Milk
编辑John T. Wilson
视频video
图书封面Titlebook: Drugs in Breast Milk;  John T. Wilson Book 1981 ADIS Press 1981 research
描述Both physicians and the lay public raise questions about drug excretion in breast milk. Enhanced interest is seen with the increase in the number of mothers who wish to breast feed. ‘Contamination‘ of breast milk by drugs and environmental chemicals imposes risks, both known and theoretical, to the infant. Drug information centres and physicians find a meagre amount of knowledge on which to base recommenda­ tions and the data which are available are often anecdotal or derived from single case reports. A critical look at both the nature and scope of our knowledge on this matter was undertaken for this review. This purpose was best served by the cooperation of pharmacologists and clinicians who have a special interest in certain classes of drugs. A unified pharmacokinetic approach was formulated to facilitate the evaluation of previous data and to offer a model for future studies. This work was, in part, published in Clinical Pharmacokinetics Vol. 5 No. I 1980. Its reception prompted this revised and expanded version and it is hoped that its critical analyses and comprehensive literature citations will foster more concerted and thorough research into drug excretion in breast milk; be
出版日期Book 1981
关键词research
版次1
doihttps://doi.org/10.1007/978-94-011-6293-7
isbn_softcover978-94-011-6295-1
isbn_ebook978-94-011-6293-7
copyrightADIS Press 1981
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Supporting Web Search with Visualizationthe nursing mother (Abramowicz, 1979), presumably because it produces milk concentrations equivalent to ‘50 % of the maternal serum levels and high enough to cause bone marrow depression in the infants’ (Hervada et al., 1978). This opinion is based on studies of a very limited number of nursing mothers.
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An Information Gap,The perspicacious pen of Lewis Thomas (1979) captures both the purpose of this monograph and our apprehension about the information gap in the field of drug excretion in human breast milk:
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Cognitive and Learning Impairments75; Blaikley et al., 1953; Waller, 1946). In the United States, the number of mothers who breast feed at the time of hospital discharge has been increasing: 25 % in 1974 (Fomon, 1974), 38% in 1975 (AAP, 1978) and 53% in 1976 (AAP, 1978). These figures compare with 35 % in Canada (AAP, 1978) and 70 %
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https://doi.org/10.1007/978-1-84800-050-6es (glands) which are subdivided into lobules. Functional units can be described as a ‘mammon’ composed of secretory cells surrounding a lumen (alveolus), ducts, and blood supply. Alveoli are connected by larger ducts which empty into collecting or lactiferous ducts. These ducts have a dilation (sin
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